P2.04-013 Prognosis Factors and Survival Analysis in Thymic Epithelial Tumors

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Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients

Background: Thymomas are rare epithelial tumors arising from thymus gland. This study aims at investigating the clinical presentation, prognostic factors and treatment outcome of forty five patients with thymoma and thymic carcinoma. Methods: Forty-five patients being histologically diagnosed with thymoma or thymic carcinoma that were treated and followed-up at a tertiary academic hospital duri...

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STAT3 expression correlates with prognosis of thymic epithelial tumors

BACKGROUND More and more evidences demonstrate the significance of Signal transducers and activators of transcription 3(STAT3) in oncogenesis and tumor development. However, little systematic researches have been reported on the correlation between STAT3 and thymic epithelial tumor (TET). METHODS Expression of STAT3 protein in 80 thymic epithelial tumors was detected by immunohistochemistry (...

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treatment results and prognostic indicators in thymic epithelial tumors: a clinicopathological analysis of 45 patients

background: thymomas are rare epithelial tumors arising from thymus gland. this study aims at investigating the clinical presentation, prognostic factors and treatment outcome of forty five patients with thymoma and thymic carcinoma. methods: forty-five patients being histologically diagnosed with thymoma or thymic carcinoma that were treated and followed-up at a tertiary academic hospital duri...

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Rare frequency of gene variation and survival analysis in thymic epithelial tumors

OBJECTIVE Thymic epithelial tumor (TET) is a rare mediastinal neoplasm and little is known about its genetic variability and prognostic factors. This study investigated the genetic variability and prognostic factors of TET. PATIENTS AND METHODS We sequenced 22 cancer-related hotspot genes in TET tissues and matched normal tissues using Ampliseq Ion Torrent next-generation technology. Overall ...

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Expression of RAGE and HMGB1 in Thymic Epithelial Tumors, Thymic Hyperplasia and Regular Thymic Morphology

Recently, a role of the receptor for advanced glycation endproducts (RAGE) in myasthenia gravis was described. RAGE and its ligand high mobility group box 1 (HMGB1) play key roles in autoimmunity and cancer. To test whether these molecules are involved in patients with thymic abnormalities we applied immunohistochemical analysis in 33 cases of thymic epithelial tumors, comprising 27 thymomas an...

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2017

ISSN: 1556-0864

DOI: 10.1016/j.jtho.2016.11.1393